WebMD provides important information about Bactrim DS Oral such as if you can you take Bactrim DS Oral when you are pregnant or nursing or If Bactrim DS Oral dangerous for children or adults over 60. Sulfamethoxazole | Trimethoprim (Bactrim® or Septra®) In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. Again, there is a thing called risk to benefit ratio when considering drugs for a pregnant woman. While it is best to not take anything while pregnant, there are sometimes when drugs are needed. Bactrim is a medication that contains trimethoprim, a substance that is generally avoided during pregnancy. Bactrim has been issued a “category C” rating from the U.S. Food and Drug Administration, meaning that it may be given to a pregnant woman only if the benefits outweigh the risks. If you don't want to take Bactrim, ask for a script for Keflex. And btw, there is next to no drug that is FDA approved and prescribed for ob patients. It is thought that the drug might contribute to birth defects by decreasing folic acid; if it is necessary for a pregnant woman to take Bactrim, a folic acid supplement at a higher-than-normal dose for a pregnant woman might be helpful. Animal studies suggest that exposure to this combination drug during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular malformations, urinary tract defects, oral clefts, and club foot. Can you take Bactrim Ds if your allergic to penicillin?If you are at all suspicious that you are pregnant please take a pregnancy test. 9. Can pregnant women take Bactrim (sulfamethoxazole and trimethoprim)?.Do not take Bactrim without first talking to your doctor if you are pregnant. do not have a dose-measuring device, ask your pharmacist where you can get one.Bactrim can be used to stop. About Common side effects of medications can become more problematic in the pregnant woman. Bactrim commonly causes nausea, vomiting and anorexia. Since pregnancy can cause these symptoms, Bactrim use can result in an increased effect in pregnant women.